About Peptic Ulcers

This site contains information from government publications about peptic ulcers that have been reformatted and reorganized. There are numerous links to the original documents.

The goal is to make the information easier to find and to allow the sharing of information between users.

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What is a peptic ulcer?

A peptic ulcer is a sore in the lining of your stomach or duodenum.* The duodenum is the first part of your small intestine. If peptic ulcers are found in the stomach, they're called gastric ulcers. If they're found in the duodenum, they're called duodenal ulcers. You can have more than one ulcer.

*Linked terms are defined in the glossary.

Many people have peptic ulcers. Peptic ulcers can be treated successfully. Seeing your doctor is the first step.

Peptic ulcers occur in the wall of the stomach and duodenum.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What are the symptoms of peptic ulcers?

A burning pain in the gut is the most common symptom. The pain

• feels like a dull ache


• comes and goes for a few days or weeks


• starts 2 to 3 hours after a meal


• comes in the middle of the night when your stomach is empty


• usually goes away after you eat

Other symptoms are

• losing weight


• not feeling like eating


• having pain while eating


• feeling sick to your stomach


• vomiting

Some people with peptic ulcers have mild symptoms. If you have any of these symptoms, you may have a peptic ulcer and should see your doctor.

A burning pain in the gut is the most common symptom.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What causes peptic ulcers?

Peptic ulcers are caused by

• bacteria called Helicobacter pylori, or H. pylori for short


• nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen


• other diseases

Nonsteroidal anti-inflammatory drugs can cause peptic ulcers.

Your body makes strong acids that digest food. A lining protects the inside of your stomach and duodenum from these acids. If the lining breaks down, the acids can damage the walls. Both H. pylori and NSAIDs weaken the lining so acid can reach the stomach or duodenal wall.

H. pylori causes almost two-thirds of all ulcers. Many people have H. pylori infections. But not everyone who has an infection will develop a peptic ulcer.

Most other ulcers are caused by NSAIDs. Only rarely do other diseases cause ulcers.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

Do stress or spicy foods cause peptic ulcers?

No, neither stress nor spicy foods cause ulcers. But they can make ulcers worse. Drinking alcohol or smoking can make ulcers worse, too.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What increases my risk of getting peptic ulcers?

You're more likely to develop a peptic ulcer if you

• have an H. pylori infection


• use NSAIDs often


• smoke cigarettes


• drink alcohol


• have relatives who have peptic ulcers


• are 50 years old or older

Having relatives with peptic ulcers puts you at risk of having them too.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

Can peptic ulcers get worse?

Peptic ulcers will get worse if they aren't treated. Call your doctor right away if you have any of these symptoms:

• sudden sharp pain that doesn't go away


• black or bloody stools


• bloody vomit or vomit that looks like coffee grounds

Call your doctor if the pain gets worse.

These could be signs that

• the ulcer has gone through, or perforated, the stomach or duodenal wall


• the ulcer has broken a blood vessel


• the ulcer has stopped food from moving from the stomach into the duodenum

These symptoms must be treated quickly. You may need surgery.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

How can I find out whether I have peptic ulcers?

If you have symptoms, see your doctor. Your doctor may

Peptic ulcers can show up on x rays.

• take x rays of your stomach and duodenum, called an upper GI series. You'll drink a liquid called barium to make your stomach and duodenum show up clearly on the x rays.


• use a thin lighted tube with a tiny camera on the end to look at the inside of your stomach and duodenum. This procedure is called an endoscopy. You'll take some medicine to relax you so your doctor can pass the thin tube through your mouth to your stomach and duodenum. Your doctor may also remove a tiny piece of your stomach to view under a microscope. This procedure is called a biopsy.

If you do have a peptic ulcer, your doctor may test your breath, blood, or tissue to see whether bacteria caused the ulcer.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

How are peptic ulcers treated?

Peptic ulcers can be cured. Medicines for peptic ulcers are

• proton pump inhibitors or histamine receptor blockers to stop your stomach from making acids


• antibiotics to kill the bacteria

Depending on your symptoms, you may take one or more of these medicines for a few weeks. They'll stop the pain and help heal your stomach or duodenum.

Ulcers take time to heal. Take your medicines even if the pain goes away. If these medicines make you feel sick or dizzy, or cause diarrhea or headaches, your doctor can change your medicines.

If NSAIDs caused your peptic ulcer, you'll need to stop taking them. If you smoke, quit. Smoking slows healing of ulcers.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

Can I use antacids for peptic ulcers?

Yes. If you have a peptic ulcer, taking antacids will

• stop the acids from working and reduce the pain


• help ulcers heal

You can buy antacids at any grocery store or drugstore. But you must take them several times a day. Also, antacids don't kill the bacteria, so your ulcer could come back even if the pain goes away.

Antacids can reduce pain and help ulcers heal.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

Can peptic ulcers come back?

Yes. If you stop taking your antibiotic too soon, not all the bacteria will be gone and not all the sores will be healed. If you still smoke or take NSAIDs, your ulcers may come back.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What happens if peptic ulcers don't heal? Will I need surgery?

In many cases, medicine heals ulcers. You may need surgery if your ulcers

• don't heal


• keep coming back


• perforate, bleed, or obstruct the stomach or
  duodenum (see Can peptic ulcers get worse?)

Surgery can

• remove the ulcers


• reduce the amount of acid your stomach makes

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What can I do to prevent peptic ulcers?

• Stop using NSAIDs. Talk with your doctor about other pain relievers.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

What can I do to lower my risk of getting peptic ulcers?

• Don't smoke.


• Don't drink alcohol.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

Peptic Ulcer Glossary

Barium (BAIR-ee-um): A chalky liquid used to coat the inside of organs so that they will show up on an x ray.

Biopsy (BYE-op-see): Removing a small piece of tissue to view under a microscope.

Duodenum (doo-AW-deh-num): The first part of your small intestine, right after your stomach.

Endoscopy (en-DAH-skoh-pee): A test to look inside the stomach and small intestine. The doctor uses a thin, flexible tube that contains a light and a tiny video camera. This device is called an endoscope.

Helicobacter pylori (HELL-ih-koh-BAK-tur py-LOH-ree): A bacterium that can damage stomach and duodenal tissue, causing ulcers. It is known as H. pylori for short.

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm

For More Peptic Ulcers Information

You can get information about peptic ulcers from the

Centers for Disease Control and Prevention
1600 Clifton Road
Atlanta, GA 30333
Phone: 1-888-MY-ULCER or (404) 639-3534
Internet: www.cdc.gov

source: http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/index.htm